Ii. Vacc~xa and Fowl Pox V~us~s*
نویسنده
چکیده
In 1942, Green, Anderson, and Smadel (2) noted that va~cinia virus appeared to have a limiting membrane and an internal structure composed of a central zone of greater density, often surrounded by four small bodies. The presence of an inner body was confirmed by Sharp e~ a2. (3). Dawson and McFarlane (4) observed that the central body resisted pepsin digestion, whereas the peripheral area became less opaque to the electron beam. They noted a limiting membrane but suggested that the satellite bodies, described by Green a 02., were artefacts. Internal structure has also been seen by others (5-7), and Peters and Nasemann (8) have illustrated and described a small, dense body located at the periphery of some viral particles, which they consider to represent developmental forms. Bang e~ 02. (9) observed a dense, central body in fowl pox virus and also noted a decrease in density at the periphery of the virus particle after treatment with pepsin. Although vaccinia (10, 11) and fowl pox (12) viruses have previously been identified in sectioned tissues, the relatively thick sections employed and the distortion produced by removal of the embedding plastic with solvents have tended to obscure details of viral structure. More recently, Gaylord and Melnick (13), employing thinner sections without removal of methacrylate, noted several forms of vaccinia virus, including "empty circles" and "circles filled with homogeneous material of low electron density," as well as internal structures described as granules, bars, and dumbbells.
منابع مشابه
Seroprevalence of Fowl Pox Antibody in Indigenous Chickens in Jos North and South Council Areas of Plateau State, Nigeria: Implication for Vector Vaccine
Fowl pox is a viral disease of domestic and wild birds. The large size of the genome makes it a useful vector for recombinant DNA technology. Although the disease has been described in both commercial and indigenous chickens in Nigeria, data are limited on seroprevalence in free range chickens. Such data are, however, important in the design and implementation of fowl pox virus vector vaccine. ...
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